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However, given the results reported in previous studies (2,25,31-33) that used moderate/high doses of vitamin B12, it should be possible to demonstrate the non-inferiority of the oral treatment with this power level

After grinding the tissue, applying low-temperature ultrasonication and settling, the supernatant was collected by centrifugation

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While our study highlights the promising effects of mannose based on preclinical data, it is important to note that these findings have not yet been confirmed in human studies